Disruptive technology in the life sciences has changed the landscape of bio-technology and bio-defence. If we consider bio-defence technology in particular, there are several advances which will likely alter how we conceive of defence and our medical counter measure options. Three major technologies: Virus Like Particles, 3D bio-printers and MIT's 4D self assembling and programmable matter technologies, will likely revolutionize bio-defence.
|Photo: www.infowars.com (nano particles used in untested H1N1 Swine Flu Vaccines|
While preventing proliferation of WMD is a noble cause, advancements, specifically in offensive biological weapon development and deployment platforms, which in some sectors of BW has resulted in 'de-skilling,' make proliferation and acquisition more likely. We simply can not afford to continue countering the threat of BW to our forces with current drug development models, outdated non-proliferation treaties and highly limited methodologies. If we compare developments in the chemical weapon field Johnathan B. Tucker notes in his paper entitled, "The Future of Chemical Weapons:" "At the same time that the process of economic globalization is undermining traditional nonproliferation measures such as export controls, a number of emerging chemical technologies have the potential to transform the nature of the CW threat as well. The pharmaceutical industry, for example, uses a technique called 'combinatorial chemistry' to discover promising drug candidates. This method involves the automated mixing and matching of molecular building blocks to generate a 'library' containing thousands of structurally related compounds, which are then screened for a desired pharmacological activity such as the ability to inhibit a key enzyme. Although harmful substances discovered in this manner typically have no therapeutic value and are set aside, it would be fairly easy to 'mine' a combinatorial database to identify highly toxic compounds that could be developed into CW agents.According to a group of experts convened by the International Union of Pure and Applied Chemistry (IUPAC) to discuss the implications of emerging technologies for the CWC, 'Some new chemicals found by data base mining will have toxicity characteristics that could lead to their being considered as chemical weapon agents.' Before a new toxic chemical can be turned into an effective weapon, however, it must meet a number of additional requirements, including stability in long term storage, an appropriate degree of volatility or persistence to ensure its effective dissemination, a low cost production method, and the availability of medical antidotes to protect the attacker's own troops." (See: http://www.thenewatlantis.com/publications/the-future-of-chemical-weapons) I would argue that disruptive technologies will witness, in the near future, the ability to rather swiftly overcome the above mentioned technical threshold issues.
Additionally, our ability to bio-print vaccines and medical counter-measures will likely increase research and development and substantially decrease manufacturing and delivery times. In terms of drug development to counter the threat BW poses to the war fighter, nano particle vaccine research and development has been on going for the past several years and is a disruptive technology which will substantially change how we deliver vaccines and other drugs. Drug development is only one sector within bio-defence to be revolutionized, it is imperative we consider technologies thus far unrelated to preventing biological weapon deployment in mass casualty scenarios. Advanced BW delivery platforms such as Micro Aerial Vehicle (MAV) delivery, requires a different set of counter-measures and an understanding of and appreciation for how this technology could be utilized for purposes beyond surveillance and intelligence collection.