Recently, a paper entitled: Rethinking the development of Ebola treatments by Rajesh Gupta, was published in The Lancet. The paper stipulates:
In order to take full advantage of this opportunity we need protocols and evaluations in step with the pace of accelerated discovery. We need to rethink evaluation processes in light of far more agile drug and drug platform discovery and development. Not only will drug research and development on Ebola vaccines and therapeutics prove advantageous to other emerging disease but will likely revolutionize fundamental aspects of this. One example is of course DARPA and Medicago's one month challenge to produce millions of vaccines. Immuno-therapies are likely to gain a strong foothold due to application to Ebola research in markets they held lesser positions. Additionally, advances in delivery such as nano vaccines and VLP's (virus like particles) as a delivery platform for gene therapy and other therapeutics is likely to become a serious technology a range of applications perhaps not considered for emergency use. The most recent discovery announced by MIT "In a paper published July 27 in the journal PLoS One, the researchers tested their drug against 15 viruses, and found it was effective against all of them — including rhinoviruses that cause the common cold, H1N1 influenza, a stomach virus, a polio virus, dengue fever and several other types of hemorrhagic fever. The drug works by targeting a type of RNA produced only in cells that have been infected by viruses. “In theory, it should work against all viruses,” says Todd Rider, a senior staff scientist in Lincoln Laboratory’s Chemical, Biological, and Nanoscale Technologies Group who invented the new technology." (Source: http://www.carbonated.tv/lifestyle/new-drug-could-cure-nearly-any-viral-infection) These types of discoveries which move far away from one bug one drug, an issue which has haunted bio-defence could well be an obsolete approach given the revolution in drug discovery we are currently witnessing.
Dr.Jill Bellamy is an internationally recognized expert on biological warfare and defence. She has formerly advised NATO and for the past seventeen years has represented a number of bio-pharmaceutical and government clients working on procurement strategy between NATO MS and Washington DC. Her private government relations consultancy Warfare Technology Analytics is based in the Netherlands. Dr. Bellamy's articles have appeared in the National Review, The Wall Street Journal, The Washington Post, The Sunday Times of London, Le Temps, Le Monde and the Jerusalem Post among other publications. She is a CBRN SME with the U.S. Department of Defence, Chemical, Biological, Radiological and Nuclear Defence Information Analysis Center and CEO of Warfare Technology Analytics.